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What’s the Best Treatment for Major Depressive Disorder?

man with head in hands talks with therapist about the best treatment for major depressive disorder

Depression can impact every part of your life. Whether you’re struggling with work, school, relationships, or daily tasks, depression can make everything feel more difficult. If you’re looking into your treatment options for major depressive disorder (MDD), you might wonder what the best treatment for it is. At TRU Wellness Center, you’ll find major depressive disorder treatment services in Minnesota and Arizona that can help you manage symptoms and get back to living your best life.

Call 888.680.7025 today if you’re ready to get started.

What Is Major Depressive Disorder?

Major depressive disorder is a mental health condition that is more than just feeling down or having a bad day—MDD can significantly impact an individual’s daily functioning and quality of life.

The symptoms of MDD can vary from person to person, but may include:

  • Persistent feelings of sadness, emptiness, or hopelessness
  • Loss of interest in previously enjoyable activities
  • Changes in sleep patterns (sleeping too much or too little)
  • Changes in appetite and weight (eating too much or too little)
  • Difficulty concentrating and making decisions
  • Feelings of guilt, worthlessness or self-blame
  • Physical symptoms such as headaches or stomachaches without a clear medical cause
  • Suicidal thoughts or behaviors

If you’re experiencing these symptoms, talking to a mental health professional can help you get a proper diagnosis and develop the best treatment plan for major depressive disorder. Treatment can make a difference.

The Best Treatment Options for Major Depressive Disorder

First, it’s important to note that there’s no one-size-fits-all treatment for MDD. Each person’s experience with depression is unique, and different treatments may work better for some individuals than others. However, there are some common treatment options that have been found to be effective for managing MDD symptoms.


Talking one-on-one with a therapist or counselor can be helpful for managing MDD. Through therapy, you can learn coping strategies for dealing with negative thoughts and emotions, develop healthier habits, and improve your overall well-being. Different types of counseling that can help those struggling with depression may include cognitive-behavioral therapy (CBT), person-centered therapy, or even family therapy.

Ketamine Therapy

In cases of severe or treatment-resistant depression, ketamine therapy may be an option. This involves receiving a controlled dose of the anesthetic drug ketamine through IV infusion. Studies have shown promising results for using ketamine to treat MDD, with some patients experiencing significant improvements in their symptoms within just a few hours.


Antidepressant medications are often prescribed as part of a comprehensive treatment plan for MDD. These medications can help regulate mood and decrease symptoms of depression. However, it’s important to note that medication is not a cure for depression and may not work for everyone.

Lifestyle Changes

Making positive changes in your daily life can also be helpful in managing MDD symptoms. This might include regular exercise, healthy eating habits, getting enough sleep, and practicing relaxation techniques such as yoga or meditation.

Reach Out to TRU Wellness Center for Major Depressive Disorder Treatment Services

At TRU Wellness Center, we offer a range of treatment options for major depressive disorder. Our team of mental health professionals will work with you to develop an individualized treatment plan that best meets your needs and goals. Whether you’d benefit most from ketamine therapy, cognitive-behavioral therapy, or a combination of approaches, we’re dedicated to helping you find relief from the symptoms of MDD and live a fulfilling life.

Call 888.680.7025 or contact TRU Wellness Center online today to get started.